Neurorepair 2024 | Program Monday

November 18th, 2024

Program Monday

Congress hall
09:00–10:30 am

Stroke-induced changes in glia function and their modulation

Details

Stroke-induced changes in glia function and their modulation

Introduction
Maria Adele Rüger (Cologne, Germany)

Role of microglial potassium channels in neuropathology
Christian Madry (Berlin, Germany)

Regulatory impact of ischemic astrocytes on microglia – the role of HCN-channels
Sabine U. Vay (Cologne, Germany)

Role of reactive astrocytes in stroke
Gabor Petzold (Bonn, Germany)

Microglia proliferation and function after stroke
Karen Gertz (Berlin, Germany)

Conference room
09:00–10:30 am

Glucose and lipid metabolic regulation and diabetic ischemic stroke

Details

Glucose and lipid metabolic regulation and diabetic ischemic stroke

White matter injury after stroke in the context of diabetes
Jun Chen (Pittsburgh, USA)

Role of exosomes and microRNAs in diabetic stroke
Poornima Venkat (Detroit, USA)

Alpha-linolenic acid in the protection of cerebral ischemic stroke
Nicolas Blondeau (Sophia Antipolis, France)

Caloric restriction induces metabolic reprogramming of CD4+ T cells after ischemic stroke
Peiying Li (Shanghai, China)

Meeting room
09:00–10:30 am

Lumen of the endoplasmic reticulum as foundation of protective and regenerative therapies for stroke and neurodegeneration

Details

Lumen of the endoplasmic reticulum as foundation of protective and regenerative therapies for stroke and neurodegeneration

Introduction to neuronal ER and Neuronal Autophagy
Marijn Kuijpers (Nijmegen, The Netherlands)

The role of KDEL receptors in stroke and neurodegeneration and insights into biology and secretion
Brandon K. Harvey (Baltimore , USA)

ER pleiotropic protein MANF expression upregulation in immune cells in ischemic human and rodent brain: therapeutic implications
Mikko Airavaara (Helsinki, Finland)

Novel approaches for the treatment of neurological diseases (multiple sclerosis, ALS)
Merja Voutilainen (Helsinki, Finland)

10:30-11:00 am | Coffee break

Congress hall
11:00 am–12:30 pm

Microvessel and endothelial beta 1-integrins and their roles in permeability barrier fidelity acutely in focal ischemia

Details follow

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Details follows

Conference room
11:00 am–12:30 pm

Recent progress in intracerebral hemorrhage research

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Recent progress in intracerebral hemorrhage research

Introduction
Marietta Zille (Vienna, Austria)

Intracerebral hemorrhages in mutant KRAS-induced mouse bAVMs
Eunhee Kim (Houston, USA)

Role of Immature Brain-Specific Microglia in Germinal Matrix Hemorrhage-Intraventricular Hemorrhage
Che-Feng Chang (Taipei, Taiwan)

The role of microglia in hematoma clearance
Jian Wang (Zhengahou, China)

CH25H and 25HC promote recovery after induction of intracerebral haemorrhage
Catherine Lawrence (Manchester, UK)

Meeting room
11:00 am–12:30 pm

Early brain perturbations contribute to long-term brain aging

Details

Early brain perturbations contribute to long-term brain aging

Endocannabinoid-mediated rescue of somatosensory cortex activity, plasticity and related behaviors following an early in life concussion
Christophe Duboi (Bordeaux, France)

Cerebral blood vessel adaptations to repeated hypoxia in the southern elephant seal: a new look into the neurodegenerative process
Jerome Badaut (Bordeaux, France)

Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction
Paul R. Perrito (Indianapolis, USA)

Wild-derived mouse strains improve preclinical translation of aging and neurodegeneration studies
Kristen D. Onos (Bar Harbor, USA)

12:30-01:30 pm | Lunch break

Congress hall
01:30–03:00 pm

Shining light on neuronal plasticity after stroke

Details

Shining light on neuronal plasticity after stroke

Brain-wide circuit dynamics of post-stroke recovery after optogenetic stimulation
Michelle Cheng (Palo Alto, USA)

Activity-dependent neuroprotection induced by gamma-range stimulation in the acute phase after stroke
Matilde Balbi (Brisbane, Australia)

Closing the loop from neuronal rewiring to functional recovery after stroke
Anna-Sophia Wahl (Zurich, Switzerland)

Combining robotic rehabilitation and neuromodulation after stroke: innovative approaches in a mouse model
Cristina Spalletti (Pisa, Italy)

Conference room
01:30–03:00 pm

Inflammation and the brain 1: mechanisms
Selected from submitted abstracts

Details

Inflammation and the brain 1: mechanisms | Selected from submitted abstracts

Distinct roles of microglial interleukin-1 alpha and interleukin-1 beta after experimental ischaemic stroke
Alba Grayston (Manchester, UK)

Neuroinflammatory Impact of SARS-CoV-2 Infection Superimposed on Preexisting Experimental Vascular Dementia
Grant Talkington (New Orleans, USA)

The impact of clonal hematopoiesis on neuroinflammation after ischemic stroke in a chimeric bone marrow mouse model
Polina Bugaeva (Berlin, Germany)

Ischemic stroke-induced alpha-synuclein pathology contributes to vascular inflammation and impaired angiogenesis
Tizibt Ashine Bogale (Milan, Italy)

Investigating Peripheral Immune Changes in Post Stroke Cognitive Decline
Natasha Carmichael (Manchester, UK)

T cells are activated antigen-specifically in the brain of mice with Alzheimer’s disease
Juliane Gellrich (Greifswald, Germany)

Meeting room
01:30–03:00 pm

Drug Delivery to the Brain: The Next Frontier for Development of Neuroprotective Therapies to Treat Ischemic Stroke

Details

Drug Delivery to the Brain: The Next Frontier for Development of Neuroprotective Therapies to Treat Ischemic Stroke

Drug Delivery across the Blood-Brain Barrier: New Perspectives
Gert Fricker (Heidelberg, Germany)

Targeting Blood-Brain Barrier Transporters for Delivery of Neuroprotective Small Molecule Drugs to the Ischemic Brain
Patrick Ronaldson (Tuscon, USA)

Cell-Based Neuroprotective Therapies for Stroke: Guided Delivery via Imaging
Miroslaw Janowski (Baltimore, USA)

It’s all in your head: stroke, vascular dementia and COVID-19
Gregory Bix (New Orleans, USA)

Poststroke activation of RNA m6A demethylase FTO by NADPH reduces brain damage and promotes functional recovery after stroke
Suresh Mehta (Wisconsin, USA)

03:00-03:30 pm | Coffee break

Congress hall
03:30–05:20 pm

Opening ceremony and presidential lecture

Details

Opening ceremony and presidential lecture

Closing the gap to the clinic: The anti-IL-17 multicenter preclinical stroke trial
Tim Magnus (Hamburg, Germany)

Heterogeneity and Harmonization: lessons from the anti-CD49d multicenter preclinical stroke trial
Liesz Arthur (Munich, Germany)

SPAN and SPRINT: The evolution of multicenter preclinical stroke trials moderated discussion
Ayata Cenk (Boston, USA)

moderated discussion

05:20-05:30 pm | Short break

Congress hall
05:30–06:50 pm

Hot News 1

Details

Hot News 1

Targeting Hypoxia-Inducible Protein 2 Promotes Immunosuppression of Brain-Infiltrated Monocytes as a Therapy for Ischemic Stroke
Weijie Chen (Shanghai, China)

The neuro-immunomodulatory effect of gut microbiota-derived secondary bile acids in stroke
Rosa Delago (Munich, Germany)

Extremely low-frequency electromagnetic stimulation (ELF-EMS) exhibits neuroprotective and immunomodulatory effects on ischemia/reperfusion models
Amanda Moya-Gomez (Diepenbeek, Belgium)

Conference room
05:30–06:50 pm

Hot News 2

Details

Hot News 2

A randomized controlled trial investigating the impact of probiotic intervention on children diagnosed with autism spectrum disorder
Ling Zhang (Zhengzhou, China)

Cross-circulation thrombectomy for acute middle cerebral artery occlusion from dislodged thrombus of a giant ruptured internal carotid aneurysm
Shanshan Cao (Shanghai, China)

Functional Connectivity Change Following Stroke in an Ovine Model
Tracy Farr (Nottingham, UK)

The Impact of Hollow Fiber Bioreactor Pore Size on Dental Pulp Stem Cells Extracellular Vesicle Production and Function
Paula M. Pincela Lins (Diepenbeek, Belgium)

Harmonizing behavioural primary outcome assessment across different raters to reduce experimental biases in a multicentre pre-clinical randomized controlled trial in ischemic stroke
Stefano Fumagalli (Milan, Italy)

Meeting room
05:30–06:50 pm

Hot News 3

Details

Hot News 3

MicroRNAs as mediators of endogenous mechanisms involved in brain adaptation to ischemic insult
Giuseppe Pignataro (Naples, Italy)

The effect of estradiol, prolactin and combination on SH-SY5Y cell under excitotoxicity conditions
Raquel Artíguez Sánchez (Mexico City, Mexico)

Neuroprotective Effects of Lithium in a Valproic Acid-Induced Rat Model of Autism Spectrum Disorder
Yi Chen (Zhengzhou, China)

Neurotoxicity of hyperphosphorylated tau oligomers linked to Alzheimer’s disease
Hong-Ru Chen (Taipei, Taiwan)

From mesenchymal stromal cell secretome to synthetic cocktail: identification of protective mediators for long term protection after traumatic brain injury
Francesca Pischiutta (Milan, Italy)

Status: August 2024

>> Program Tuesday

Congress hall 09:00–10:30 am

Conference room 09:00–10:30 am

Meeting room 09:00–10:30 am

10:30-11:00 am | Coffee break

Congress hall 11:00 am–12:30 pm

Conference room 11:00 am–12:30 pm

Meeting room 11:00 am–12:30 pm

12:30-01:30 pm | Lunch break

Congress hall 01:30–03:00 pm

Conference room 01:30–03:00 pm

Meeting room 01:30–03:00 pm

03:00-03:30 pm | Coffee break

Congress hall 03:30–05:20 pm

05:20-05:30 pm | Short break

Congress hall 05:30–06:50 pm

Conference room 05:30–06:50 pm

Meeting room 05:30–06:50 pm

Congress hall
09:00–10:30 am

Conference room
09:00–10:30 am

Meeting room
09:00–10:30 am

Congress hall
11:00 am–12:30 pm

Conference room
11:00 am–12:30 pm

Meeting room
11:00 am–12:30 pm

Congress hall
01:30–03:00 pm

Conference room
01:30–03:00 pm

Meeting room
01:30–03:00 pm

Congress hall
03:30–05:20 pm

Congress hall
05:30–06:50 pm

Conference room
05:30–06:50 pm

Meeting room
05:30–06:50 pm