Neurorepair 2024 | Program Wednesday

November 20th, 2024

Program Wednesday

Congress hall
08:30–09:45 am

Improving stroke outcome
Selected from submitted abstracts

Improving stroke outcome | Selected from submitted abstracts

08:30–08:45 am | Intestinal epithelial stem cell tranplants improve acute and chronic stroke impairments
Farida Sohrabji (Bryan, USA)

08:45–09:00 am | Torpor is cerebroprotective after stroke
Eric Landsness (Saint Louis, USA)

09:00–09:15 am | Discovering new blood biomarkers of neuroplasticity associated to rehabilitation outcome after stroke
Anna Rosell (Barcelona, Spain)

09:15–09:30 am | Subacute cathodal transcranial direct current stimulation rescues secondary thalamic neurodegeneration after cortical stroke in mice
Stefan Blaschke (Cologne, Germany)

09:30–09:45 am | Discussion

Conference room
08:30–09:45 am

Inflammation and the brain 2: therapeutic approaches
Selected from submitted abstracts

Details

Inflammation and the brain 2: therapeutic approaches | Selected from submitted abstracts

08:30–08:45 am | The effect of tocilizumab in animal models of ischaemic stroke: a systematic review and meta-analysis
Torsten Rackoll (Berliln, Germany)

08:45–09:00 am | Netrin-1 alleviates blood-brain barrier dysfunction via pericyte-microglia interaction after cerebral ischemia-reperfusion injury
Qiang Li (Shanghai, China)

09:00–09:15 am | Impact of anti-platelet and anti-coagulant therapies in a microfluidic model of thromboinflammation
Astride Perrot (Paris, France)

09:15–09:30 am | St3gal5-mediated glycosylation retains CD177+ neutrophils to restrict neuroinflammation in the acute injured brain
Tingting Huang (Shanghai, China)

09:30–09:45 am | PIWIL proteins and piRNAs may play a role in reducing neuroinflammation and stabilizing genomic integrity post-stroke
Rohan Patil (Naples, Italy)

Meeting room
08:30–09:45 am

Novel concepts for optimization of therapeutic approaches
Selected from submitted abstracts

Details

Novel concepts for optimization of therapeutic approaches | Selected from submitted abstracts

08:30–08:45 am | Vectorization of Therapeutic Agents via Click Chemistry Mediated Grafting of the Finger Domain of TPA
Camille Delahaie (Caen, France)

08:45–09:00 am | Functionalization of antioxidant cerium oxide nanoparticles with DNase I to improve ischemic stroke treatment
Norhane Salah (Paris, France)

09:00–09:15 am | Network-based drug repurposing strategy for stroke treatment: A broad therapy for a specific patient
Ana Casas (Essen, Germany)

09:15–09:30 am | Optimization of Cell Penetrating Poly-Arginine Peptides to Provide a Superior Therapeutic Index Against Severe Excitotoxic Insults In Vitro
Joe Tauskela (Ottawa, Canada)

09:30–09:45 am | Development of therapeutic and diagnostic strategies targeting the neurovascular unit following exposure to organophosphorus nerve agents
Mélanie Lagadec (Caen, France)

09:45-10:30 am | Coffee break

Congress hall
10:30 am–12:00 pm

Tissue-type Plasminogen Activator (tPA): Beyond Fibrinolysis

Details

Tissue-type Plasminogen Activator (tPA): Beyond Fibrinolysis

10:30–11:00 am | Targeting tPA-dependent NMDA Receptor Signaling to Improve Stroke Treatment
Denis Vivien (Caen, France)

11:00–11:20 am | New advances in experimental thrombolytic formulations for the treatment of ischaemic stroke
Francisco Campos (Santiago de Compostela, Spain)

11:20–11:40 am | Leptomeningeal Collaterals Regulate rtPA-mediated Reperfusion in Ischemic Stroke
Susanne Wegener (Zurich, Switzerland)

11:40–12:00 pm | TGD001, a novel thrombolytic agent with improved efficacy in preclinical models of acute ischemic stroke and thrombotic thrombocytopenic purpura
Steven de Maat (Utrecht, Netherlands)

Conference room
10:30 am–12:00 pm

Hemorrhagic stroke II: novel models and mechanisms
Selected from submitted abstracts

Details

Hemorrhagic stroke II: novel models and mechanisms | Selected from submitted abstracts

10:30–10:45 am | Brain endothelial cell death induced by experimental hemorrhagic stroke in vitro involves ferroptosis, necroptosis, and autophagy
Maulana Ikhsan (Lhokseumawe, Indonesia)

10:45–11:00 am | Optimising the use of Zebrafish to study Inflammasomes for Intracerebral Haemorrhage Research
Poornima Geemon (Manchester, UK)

11:00–11:15 am | Toward Novel Intracerebral Haemorrhage Stroke Models by Endovascular Approach in Swine
Teresa Gasull (Badalona, Spain)

11:15–11:30 pm | Using zebrafish larvae to study the role of cholesterol 25-hydroxylase in haematoma clearance after intracerebral haemorrhage
Abigail Bennington (Manchester, UK)

11:30–11:45 pm | Bacterial Translocation After Hemorrhagic Stroke: Effect of the hematoma size and the absence of TLR4
Jesús Pradillo (Madrid, Spain)

11:45–12:00 pm | Context-Specific Roles of CNS-Associated Macrophages in Intracerebral Hemorrhage
Mathys Bellemain-Sagnard (Caen, France)

Meeting room
10:30 am–12:00 pm

Neuroprotection and immunomodulation for stroke in post-thrombectomy era

Details

Neuroprotection and immunomodulation for stroke in post-thrombectomy era

10:30–11:00 am | Neuroprotection and endogenous neuroregeneration after ischemia
Raphael Guzman (Basel, Switzerland)

11:00–11:20 am | Acute cerebroprotection in large animal models
Johannes Boltze (Coventry, UK)

11:20–11:40 am | Endovascular model of stroke in swine to recapitulate neurointerventions adjunct to thrombectomy
Dominika Golubczyk (Olsztyn, Poland)

11:40–12:00 pm | Biologics-based immunomodulation in patients with stroke
Dileep Yavagal (Miami, USA)

12:00-01:00 pm | Lunch break

01:00–02:30 pm | Poster viewing

Congress hall
02:30–04:00 pm

Defining a role for the immune system in stroke: preclinical and clinical evidence

Details

Defining a role for the immune system in stroke: preclinical and clinical evidence

02:30–03:00 pm | Clinical investigation of early and long-term changes in systemic immune profiles after ischaemic stroke and their relationship to cognitive decline
Stuart Allan (Manchester, United Kingdom)

03:00–03:20 pm | Immune and non-immune effects of Interleukin-17 on stroke recovery
Mathias Gelderblom (Hamburg, Germany)

03:20–03:40 pm | Inflammation in the brain fosters plasticity and regeneration after stroke in mice
Harms Christoph (Berlin, Germany)

03:40–04:00 pm | Immunophenotyping of lymphocyte subsets in intracranial blood and cerebrospinal fluid from acute stroke patients
Ann Stowe (Lexington, USA)

Conference room
02:30–04:00 pm

Mesenchymal Stem Cell-derived Extracellular Vesicles: a Potential New Tool for Cerebral Ischemia

Details

Mesenchymal Stem Cell-derived Extracellular Vesicles: a Potential New Tool for Cerebral Ischemia

02:30–03:00 pm | Role of polymorphonuclear neutrophils in mediating neuroprotection post-ischemia
Dirk Hermann (Essen, Germany)

03:00–03:20 pm | Mesenchymal Stem Cell-derived Extracellular Vesicles: a Potential New Tool in Regenerative Medicine
Bernd Giebel (Essen, Germany)

03:20–03:40 pm | Mesenchymal Stem Cell-derived Extracellular Vesicles: a New Therapeutic Tool for the Aged Brain after Cerebral Ischemia
Aurel Popa-Wagner (Craiova, Romania)

03:40–04:00 pm | Cell-derived extracellular vesicles as interorgan messengers under conditions of ischemic stroke
Thorsten Doeppner (Giessen, Germany)

Meeting room
02:30–04:00 pm

Early brain perturbations contribute to long–term brain aging

Details follow

Early brain perturbations contribute to long–term brain aging

02:30–03:00 pm | Endocannabinoid-mediated rescue of somatosensory cortex activity, plasticity and related behaviors following an early in life concussion
Christophe Duboi (Bordeaux, France)

03:00–03:20 pm | Cerebral blood vessel adaptations to repeated hypoxia in the southern elephant seal: a new look into the neurodegenerative process
Jerome Badaut (Bordeaux, France)

03:20–03:40 pm | Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction
Paul R. Territo (Indianapolis, USA)

03:40–04:00 pm | Early astrocyte responses drive long term consequences after mild Traumatic Brain Injury/Concussion
Stefanie Robel (Birmingham, UK)

04:00-04:30 pm | Coffee break

Congress hall
04:30–05:30 pm

ISN&N closing session

Details

tba

Therapeutic brain protection and repair: Feasible or ficticious?
Ulrich Dirnagl (Berlin, Germany)

Status: August 2024

Congress hall 08:30–09:45 am

Conference room 08:30–09:45 am

Meeting room 08:30–09:45 am

09:45-10:30 am | Coffee break

Congress hall 10:30 am–12:00 pm

Conference room 10:30 am–12:00 pm

Meeting room 10:30 am–12:00 pm

12:00-01:00 pm | Lunch break

01:00–02:30 pm | Poster viewing

Congress hall 02:30–04:00 pm

Conference room 02:30–04:00 pm

Meeting room 02:30–04:00 pm

04:00-04:30 pm | Coffee break

Congress hall 04:30–05:30 pm

supported by

Congress hall
08:30–09:45 am

Conference room
08:30–09:45 am

Meeting room
08:30–09:45 am

Congress hall
10:30 am–12:00 pm

Conference room
10:30 am–12:00 pm

Meeting room
10:30 am–12:00 pm

Congress hall
02:30–04:00 pm

Conference room
02:30–04:00 pm

Meeting room
02:30–04:00 pm

Congress hall
04:30–05:30 pm